Children’s Hospital of Philadelphia – Compounding Pharmacies

Precis was tasked with the design of renovations to multiple compounding pharmacies in five locations for Children’s Hospital of Philadelphia (CHOP). The renovations were required to support compliance with the updated USP 795 Non-Sterile Preparations, USP 797 Sterile Preparations, and USP 800 Hazardous Drugs guidelines.

The renovated pharmacies included three in the Main Hospital, two in the Buerger Center for Advanced Pediatric Care, one in the Wood Center for Fetal Diagnosis and Treatment, one in the King of Prussia Specialty Care & Surgery Center, and one in the Voorhees Specialty Care & Surgery Center.

Pharmacy spaces included sterile low, medium, and high-risk non-hazardous compounding; hazardous drug and gene therapy compounding; non-sterile hazardous compounding; oral compounding; Investigational Drugs Services (IDS) space; and accommodations for Riva robotic IV automation compounding systems.

Ancillary spaces included receiving work rooms with refrigerators, freezers, and pyxis; C2 safe/pyxis areas; quarantine, IV storage, general storage, high-density rolling storage, and high-density automated vertical storage; anesthesia prep work rooms; holding rooms and ante rooms; order entry, office, audit, purchasing, and staff support areas. In the Voorhees facility, the scope also included design of a temporary pharmacy to be used during renovations to the permanent pharmacy.