Center for Breakthrough Medicines – 411 Innovations Labs Complex

Precis was tasked with programming multiple buildings within the Center for Breakthrough Medicines (CBM) 411 Innovations Labs complex in King of Prussia, Pennsylvania. The CBM is an advanced therapy-focused contract development manufacturing organization (CDMO) dedicated to delivering life-changing patient treatments.

Precis provided programming for viral vector, cell therapy, filling, plasmid, and mRNA manufacturing; myco, molecular, quality control (QC), next-generation sequencing (NGS), virology, flow cytometry, and environmental monitoring testing labs; and warehouse and support areas.

Precis was responsible for defining user requirements to be able to develop a conceptual floor plan and equipment layout. Tasks included participating in programming meetings with the users to walk through the process and define space requirements. In addition to the floor plan, room cards were developed to define equipment, utilities, and other design requirements needed within each room. Deliverables included a programming questionnaire, programming layout, equipment list with consumption requirements, and the development of room cards. After completing concept design, Precis continued to provide design support to the architectural and mechanical, electrical, and plumbing (MEP) teams along with providing GMP expertise.