Kremers Urban Pharmaceuticals – Oral Solid Dosage (OSD) Manufacturing Suite

Precis designed a 10,000-sf oral solid dosage (OSD) manufacturing suite expansion for Kremers Urban Pharmaceuticals, a specialty generic pharmaceutical company. The architectural design included layout, code analysis for high hazard occupancy, and specifications for partition systems and finishes. The engineering design included mechanical, electrical, and plumbing systems required for solvent dispensing, solution preparation, and controlled humidity, along with HVAC systems and ductwork, electrical distribution, and chilled water, steam, and compressed air distribution. The design also included spaces for future expansion.

The manufacturing suite incorporated Glatt GPCG 120s with three-column Wurster coaters and thermal oxidizers, drum and bowl inverters for bin loading, bin blending and handling (1,000L), a central chilled water plant, a waste neutralization system, and support spaces including protected and utility corridors, a wash area, and USP water system.

In addition to the manufacturing space design, the team performed a central utility upgrade, adding a new 1,200-ton chiller plant, as well as a new central batch-type waste neutralization system.

Image © Ivan Milovanov / IM Imagery OU